GEDV (Global End-Diastolic Volume) and GEDI (Global End-Diastolic Volume Index) are a cardiac preload assessment measures. The latter being GEDV divided by the body surface area in square meters.
Being a volime they are independent of the heart compliance and all the adjoining structures, giving a more accurate picture of preload than a pressure.
Unfortunately they can’t distinguish between the left and right sides of the heart, giving a incomplete picture of the distribution of preload between the chambers.
They are obtained by the transpulmonary thermodilution method as given by the PiCCO and VolumeView devices.
- The patient must have a CVC and special designed arterial line connect to a PiCCO or EV1000 monitor.
- Obtained after a thermodilution curve analysis, usually with a cold saline bolus, so it isn’t continuous.
Global End-Diastolic Volume as a Variable of Fluid Responsiveness During Acute Changing Loading Conditions; Jochen Renner, Mathias Gruenewald, Philip Brand, Markus Steinfath, Jens Scholz, Georg Lutter, Berthold Bein; Journal of cardiothoracic and vascular anesthesia;2007;21(5):650–654) ↩